Measles Lesson
Step 8: Results Video 📊
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About this Video
Learn about the different groups the researchers examined and how their antibodies responded. Also explore the different control groups the researchers included to make sure that their experimental design was appropriate and to make sure there were no confounding factors.
Transcript
So what did they find? So there’s some really cool results here. Now on the Y-axis we have the change in antibodies. And this is kind of like the diversity of antibodies in a person’s body. And we’re going to draw a dotted line here and this is zero. So this is where we have no change in the antibodies before and after getting infected. Below that the antibodies would decrease and above that it would increase. So I’m going to start with the kids who actually got measles. This is what their data looks like. So this is for mild cases and this is for severe cases. So the kids who got measles had a decrease in the diversity of their antibodies and these are the kids who got sick. Now we have a group that got vaccinated – a control group. So this is to show that if you get vaccinated your antibodies go up. Then we have another control. This is a negative control and the data looks just like this. These are the 5 kids that didn’t get infected at this school. Their antibodies didn’t change at all and that’s what we would expect from a negative
control – no change. After that we have three different controls to compare to and I’m just going to label them A, B, and C and the data all looks pretty much the same – all at this zero level. So there’s no change in the diversity of antibodies. So this first control is healthy kids, and they took blood at the same schedule as the kids that got sick. B, those are also healthy kids and they took blood samples yearly. And C are healthy adults, and those blood samples were taken at the same interval. So these three controls right here are to make sure that the antibodies aren’t naturally changing over time. So looking at this you can see that our antibodies decreased if they got sick. If they got a vaccine their antibodies went up. And all of our controls confirm that if nothing happens our antibodies don’t change at all. Another confirmation of the researchers results is that the monkeys that they infected with measles also showed this decrease in antibody diversity. And that was seen up to five months after they got sick.
Learn about the different groups the researchers examined and how their antibodies responded. Also explore the different control groups the researchers included to make sure that their experimental design was appropriate and to make sure there were no confounding factors.
So what did they find? So there’s some really cool results here. Now on the Y-axis we have the change in antibodies. And this is kind of like the diversity of antibodies in a person’s body. And we’re going to draw a dotted line here and this is zero. So this is where we have no change in the antibodies before and after getting infected. Below that the antibodies would decrease and above that it would increase. So I’m going to start with the kids who actually got measles. This is what their data looks like. So this is for mild cases and this is for severe cases. So the kids who got measles had a decrease in the diversity of their antibodies and these are the kids who got sick. Now we have a group that got vaccinated – a control group. So this is to show that if you get vaccinated your antibodies go up. Then we have another control. This is a negative control and the data looks just like this. These are the 5 kids that didn’t get infected at this school. Their antibodies didn’t change at all and that’s what we would expect from a negative
control – no change. After that we have three different controls to compare to and I’m just going to label them A, B, and C and the data all looks pretty much the same – all at this zero level. So there’s no change in the diversity of antibodies. So this first control is healthy kids, and they took blood at the same schedule as the kids that got sick. B, those are also healthy kids and they took blood samples yearly. And C are healthy adults, and those blood samples were taken at the same interval. So these three controls right here are to make sure that the antibodies aren’t naturally changing over time. So looking at this you can see that our antibodies decreased if they got sick. If they got a vaccine their antibodies went up. And all of our controls confirm that if nothing happens our antibodies don’t change at all. Another confirmation of the researchers results is that the monkeys that they infected with measles also showed this decrease in antibody diversity. And that was seen up to five months after they got sick.